Effects of HMGA2 on the epithelial-mesenchymal transition-related genes in ACHN renal cell carcinoma cells-derived xenografts in nude mice

Effects of HMGA2 on the epithelial-mesenchymal transition-related genes in ACHN renal cell carcinoma cells-derived xenografts in nude mice

Abstract Background The architectural transcriptional regulator high-mobility group AT-hook 2 (HMGA2) is an oncofetal protein which has been reported to be ectopically expressed in a variety of cancers. A high expression of HMGA2 in human renal cell carcinoma (RCC) is related with tumor invasiveness...

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Bibliographic Details
Main Authors: Ying Liu, Guangyao Lv, Jianxin Bai, Lingling Song, Elizabeth Ding, Lin Liu, Yuqin Tian, Qian Chen, Kai Li, Xianfeng Liu, Yan Ding
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Cancer
Subjects:
HMGA2
shRNA
Epithelial-mesenchymal transition
ACHN cells
Xenograft
Online Access:https://doi.org/10.1186/s12885-022-09537-w

Internet

https://doi.org/10.1186/s12885-022-09537-w

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