Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy

Vascular endothelial growth factors (VEGFs) bind to membrane receptors on a wide variety of cells to regulate diverse biological responses. The VEGF-A family member promotes vasculogenesis and angiogenesis, processes which are essential for vascular development and physiology. As angiogenesis can be...

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Bibliographic Details
Main Authors: Faheem Shaik, Gary A. Cuthbert, Shervanthi Homer-Vanniasinkam, Stephen P. Muench, Sreenivasan Ponnambalam, Michael A. Harrison
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/12/1673