Sex- and Genotype-Dependent Nicotine-Induced Behaviors in Adolescent Rats with a Human Polymorphism (rs2304297) in the 3′-UTR of the <i>CHRNA</i>6 Gene

Sex- and Genotype-Dependent Nicotine-Induced Behaviors in Adolescent Rats with a Human Polymorphism (rs2304297) in the 3′-UTR of the <i>CHRNA</i>6 Gene

In human adolescents, a single nucleotide polymorphism (SNP), rs2304297, in the 3′-UTR of the nicotinic receptor subunit gene, <i>CHRNA</i>6, has been associated with increased smoking. To study the effects of the human <i>CHRNA6</i> 3′-UTR SNP, our lab generated knock-in rod...

Full description

Bibliographic Details
Main Authors: Anjelica Cardenas, Yu Bai, Yasamin Hajy Heydary, Jiaqi Li, Frances M. Leslie, Shahrdad Lotfipour
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>CHRNA6</i>
locomotor activity
anxiety-like behavior
adolescent
pharmacogenetics
Online Access:https://www.mdpi.com/1422-0067/23/6/3145

Internet

https://www.mdpi.com/1422-0067/23/6/3145

Similar Items