Cross-Species Analysis of Innate Immune Antagonism by Cytomegalovirus IE1 Protein

Cross-Species Analysis of Innate Immune Antagonism by Cytomegalovirus IE1 Protein

The human cytomegalovirus (CMV) immediate early 1 (IE1) protein has evolved as a multifunctional antagonist of intrinsic and innate immune mechanisms. In addition, this protein serves as a transactivator and potential genome maintenance protein. Recently, the crystal structures of the human and rat...

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Bibliographic Details
Main Authors: Franziska Rothemund, Myriam Scherer, Eva-Maria Schilling, Johannes Schweininger, Yves A. Muller, Thomas Stamminger
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
cytomegalovirus
HCMV
RCMV
immediate early
innate immunity
IE1
Online Access:https://www.mdpi.com/1999-4915/14/8/1626

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https://www.mdpi.com/1999-4915/14/8/1626

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