Unraveling the mechanisms of intervertebral disc degeneration: an exploration of the p38 MAPK signaling pathway

Unraveling the mechanisms of intervertebral disc degeneration: an exploration of the p38 MAPK signaling pathway

Intervertebral disc (IVD) degeneration (IDD) is a worldwide spinal degenerative disease. Low back pain (LBP) is frequently caused by a variety of conditions brought on by IDD, including IVD herniation and spinal stenosis, etc. These conditions bring substantial physical and psychological pressure an...

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Bibliographic Details
Main Authors: Xingmin Zhang, Zilin Zhang, Xiaosong Zou, Yongjie Wang, Jinwei Qi, Song Han, Jingguo Xin, Zhi Zheng, Lin Wei, Tianhui Zhang, Shaokun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
p38 MAPK pathway
intervertebral disc degeneration (IDD)
extracellular matrix (ECM)
inflammation
senescence
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1324561/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1324561/full

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