10 Pre-clinical studies of sotagliflozin in hypertrophic cardiomyopathy

OBJECTIVES/GOALS: Study the regulatory role of sodium glucose co-transporter 1 (SGLT1) in cardiomyocytes and the therapeutic potential of sotagliflozin in hypertrophic cardiomyopathy (HCM) by (a) quantifying SGLT1 expression in HCM and (b) examining the impact of sotagliflozin on cardiac mechanics....

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Hlavní autoři: Rebecca Taichman, Benjamin Lee, Kenneth Margulies, Sharlene Day
Médium: Článek
Jazyk:English
Vydáno: Cambridge University Press 2024-04-01
Edice:Journal of Clinical and Translational Science
On-line přístup:https://www.cambridge.org/core/product/identifier/S2059866124000311/type/journal_article