Antidepressant Mechanism of Traditional Chinese Medicine Formula Xiaoyaosan in CUMS-Induced Depressed Mouse Model via RIPK1-RIPK3-MLKL Mediated Necroptosis Based on Network Pharmacology Analysis

Background: Depression is a stress-related disorder that seriously threatens people’s physical and mental health. Xiaoyaosan is a classical traditional Chinese medicine formula, which has been used to treat mental depression since ancient times. More and more notice has been given to the relationshi...

Full description

Bibliographic Details
Main Authors: Zhi-Yi Yan, Hai-Yan Jiao, Jian-Bei Chen, Kai-Wen Zhang, Xi-Hong Wang, You-Ming Jiang, Yue-Yun Liu, Zhe Xue, Qing-Yu Ma, Xiao-Juan Li, Jia-Xu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.773562/full