The effects of sequencing depth on the assembly of coding and noncoding transcripts in the human genome

Abstract Investigating the functions and activities of genes requires proper annotation of the transcribed units. However, transcript assembly efforts have produced a surprisingly large variation in the number of transcripts, and especially so for noncoding transcripts. This heterogeneity in assembl...

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Bibliographic Details
Main Authors: Isaac Adeyemi Babarinde, Andrew Paul Hutchins
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-022-08717-z