Saccharomyces cerevisiae goes through distinct metabolic phases during its replicative lifespan

Saccharomyces cerevisiae goes through distinct metabolic phases during its replicative lifespan

A comprehensive description of the phenotypic changes during cellular aging is key towards unraveling its causal forces. Previously, we mapped age-related changes in the proteome and transcriptome (Janssens et al., 2015). Here, employing the same experimental procedure and model-based inference, we...

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Bibliographic Details
Main Authors: Simeon Leupold, Georg Hubmann, Athanasios Litsios, Anne C Meinema, Vakil Takhaveev, Alexandros Papagiannakis, Bastian Niebel, Georges Janssens, David Siegel, Matthias Heinemann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-04-01
Series:eLife
Subjects:
replicative aging
metabolome
metabolic fluxes
metabolic modelling
Online Access:https://elifesciences.org/articles/41046

Internet

https://elifesciences.org/articles/41046

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