Deciphering the spatiotemporal transcriptional and chromatin accessibility of human retinal organoid development at the single-cell level

Deciphering the spatiotemporal transcriptional and chromatin accessibility of human retinal organoid development at the single-cell level

Summary: Molecular information on the early stages of human retinal development remains scarce due to limitations in obtaining early human eye samples. Pluripotent stem cell-derived retinal organoids (ROs) provide an unprecedented opportunity for studying early retinogenesis. Using a combination of...

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Bibliographic Details
Main Authors: Birthe Dorgau, Joseph Collin, Agata Rozanska, Veronika Boczonadi, Marina Moya-Molina, Adrienne Unsworth, Rafiqul Hussain, Jonathan Coxhead, Tamil Dhanaseelan, Lyle Armstrong, Rachel Queen, Majlinda Lako
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Genetics
Molecular biology
Neuroscience
Cell biology
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224006187

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http://www.sciencedirect.com/science/article/pii/S2589004224006187

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