AMPK Activation Is Indispensable for the Protective Effects of Caloric Restriction on Left Ventricular Function in Postinfarct Myocardium

AMPK Activation Is Indispensable for the Protective Effects of Caloric Restriction on Left Ventricular Function in Postinfarct Myocardium

Background: Caloric restriction (CR) extends lifespan in many species, including mammals. CR is cardioprotective in senescent myocardium by correcting pre-existing mitochondrial dysfunction and apoptotic activation. Furthermore, it confers cardioprotection against acute ischemia-reperfusion injury....

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Bibliographic Details
Main Authors: Bernd Niemann, Ruping Pan, Hassan Issa, Andreas Simm, Rainer Schulz, Susanne Rohrbach
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biology
Subjects:
heart failure
ischemia
caloric restriction
AMPK
mitochondria
Online Access:https://www.mdpi.com/2079-7737/11/3/448

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https://www.mdpi.com/2079-7737/11/3/448

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