The frequency of POLE-mutation in endometrial carcinoma and prognostic implications: a systemic review and meta-analysis
Background Endometrial carcinoma (EC) is classified into four distinct molecular subgroups including ultramutated DNA polymerase epsilon (POLE). POLE-mutated tumors have the best prognosis and are a promising target for immunotherapy. This meta-analysis consolidated the reported variation of POLE-mu...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Korean Society of Pathologists & the Korean Society for Cytopathology
2020-11-01
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Series: | Journal of Pathology and Translational Medicine |
Subjects: | |
Online Access: | http://www.jpatholtm.org/upload/pdf/jptm-2020-07-23.pdf |