The frequency of POLE-mutation in endometrial carcinoma and prognostic implications: a systemic review and meta-analysis

The frequency of POLE-mutation in endometrial carcinoma and prognostic implications: a systemic review and meta-analysis

Background Endometrial carcinoma (EC) is classified into four distinct molecular subgroups including ultramutated DNA polymerase epsilon (POLE). POLE-mutated tumors have the best prognosis and are a promising target for immunotherapy. This meta-analysis consolidated the reported variation of POLE-mu...

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Bibliographic Details
Main Authors: Alaa Salah Jumaah, Mais Muhammed Salim, Hawraa Sahib Al-Haddad, Katherine Ann McAllister, Akeel Abed Yasseen
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2020-11-01
Series:Journal of Pathology and Translational Medicine
Subjects:
endometrial carcinoma
gene
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2020-07-23.pdf

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