Epigenetic role of LINE-1 methylation and key genes in pregnancy maintenance

Epigenetic role of LINE-1 methylation and key genes in pregnancy maintenance

Abstract Spontaneous abortion is a pregnancy complication characterized by complex and multifactorial etiology. About 5% of childbearing women are globally affected by early pregnancy loss (EPL) and most of them experience recurrence (RPL). Epigenetic mechanisms and controlled inflammation are cruci...

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Bibliographic Details
Main Authors: Veronica Tisato, Juliana A. Silva, Fabio Scarpellini, Roberta Capucci, Roberto Marci, Ines Gallo, Francesca Salvatori, Elisabetta D’Aversa, Paola Secchiero, Maria L. Serino, Giorgio Zauli, Ajay V. Singh, Donato Gemmati
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Epigenomics
Epigenetics
Epidrugs, LINE-1 methylation
Retrotransposons
Inflammation
Cytokines
Online Access:https://doi.org/10.1038/s41598-024-53737-2

Internet

https://doi.org/10.1038/s41598-024-53737-2

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