Oligohistidine and targeting peptide functionalized TAT-NLS for enhancing cellular uptake and promoting angiogenesis in vivo

Oligohistidine and targeting peptide functionalized TAT-NLS for enhancing cellular uptake and promoting angiogenesis in vivo

Abstract Background Gene therapy has been developed and used in medical treatment for many years, especially for the enhancement of endothelialization and angiogenesis. But slow endosomal escape rate is still one of the major barriers to successful gene delivery. In order to evaluate whether introdu...

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Bibliographic Details
Main Authors: Qian Li, Xuefang Hao, Syed Saqib Ali Zaidi, Jintang Guo, Xiangkui Ren, Changcan Shi, Wencheng Zhang, Yakai Feng
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Nanobiotechnology
Subjects:
Gene carrier
Peptide
Histidine
REDV
Targeting
HUVECs
Online Access:http://link.springer.com/article/10.1186/s12951-018-0358-x

Internet

http://link.springer.com/article/10.1186/s12951-018-0358-x

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