Oligohistidine and targeting peptide functionalized TAT-NLS for enhancing cellular uptake and promoting angiogenesis in vivo
Abstract Background Gene therapy has been developed and used in medical treatment for many years, especially for the enhancement of endothelialization and angiogenesis. But slow endosomal escape rate is still one of the major barriers to successful gene delivery. In order to evaluate whether introdu...
Main Authors: | Qian Li, Xuefang Hao, Syed Saqib Ali Zaidi, Jintang Guo, Xiangkui Ren, Changcan Shi, Wencheng Zhang, Yakai Feng |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12951-018-0358-x |
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