Chitosan and Sodium Alginate Implementation as Pharmaceutical Excipients in Multiple-Unit Particulate Systems

This study aimed to prepare and evaluate pellets containing acyclovir as a model drug. Pellets were prepared by the extrusion–spheronization process. Aqueous solutions of natural marine polymers (sodium alginate, chitosan) were compared to semi-synthetic hydroxypropyl methylcellulose (HPMC) in the r...

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Bibliographic Details
Main Authors: Martina Čierna, Pavel Mučaji, Miroslava Špaglová, Mária Čuchorová, Oliver Macho
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/14/14/2822