Arylaminopropanone Derivatives as Potential Cholinesterase Inhibitors: Synthesis, Docking Study and Biological Evaluation

Neurodegenerative diseases in which the decrease of the acetylcholine is observed are growing worldwide. In the present study, a series of new arylaminopropanone derivatives with <i>N</i>-phenylcarbamate moiety (<b>1–16</b>) were prepared as potential acetylcholinesterase and...

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Bibliographic Details
Main Authors: Anna Hudcová, Aleš Kroutil, Renata Kubínová, Adriana D. Garro, Lucas J. Gutierrez, Daniel Enriz, Michal Oravec, Jozef Csöllei
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/7/1751