A more accurate method for colocalisation analysis allowing for multiple causal variants.
In genome-wide association studies (GWAS) it is now common to search for, and find, multiple causal variants located in close proximity. It has also become standard to ask whether different traits share the same causal variants, but one of the popular methods to answer this question, coloc, makes th...
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-09-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1009440 |