The Role of Irisin/FNDC5 Expression and Its Serum Level in Breast Cancer

The Role of Irisin/FNDC5 Expression and Its Serum Level in Breast Cancer

Irisin (Ir) is an adipomyokine formed from fibronectin type III domain-containing protein 5 (FNDC5), which can be found in various cancer tissues. Additionally, FNDC5/Ir is suspected of inhibiting the epithelial-mesenchymal transition (EMT) process. This relationship has been poorly studied for brea...

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Bibliographic Details
Main Authors: Kamil Cebulski, Aleksandra Piotrowska, Alicja Kmiecik, Katarzyna Haczkiewicz-Leśniak, Urszula Ciesielska, Jędrzej Grzegrzółka, Karolina Jabłońska, Hanna Romanowicz, Beata Smolarz, Piotr Dzięgiel, Marzenna Podhorska-Okołów, Katarzyna Nowińska
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
irisin
FNDC5
EMT
E-cadherin
SNAIL
SLUG
Online Access:https://www.mdpi.com/1422-0067/24/10/8628

Internet

https://www.mdpi.com/1422-0067/24/10/8628

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