Modulation of Mitochondrial Metabolic Reprogramming and Oxidative Stress to Overcome Chemoresistance in Cancer

Modulation of Mitochondrial Metabolic Reprogramming and Oxidative Stress to Overcome Chemoresistance in Cancer

Metabolic reprogramming, carried out by cancer cells to rapidly adapt to stress such as hypoxia and limited nutrient conditions, is an emerging concepts in tumor biology, and is now recognized as one of the hallmarks of cancer. In contrast with conventional views, based on the classical Warburg effe...

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Bibliographic Details
Main Authors: Rosario Avolio, Danilo Swann Matassa, Daniela Criscuolo, Matteo Landriscina, Franca Esposito
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Biomolecules
Subjects:
cancer metabolic reprogramming
oxidative stress
drug resistance
tumor necrosis factor receptor associated protein 1 (trap1)
heat shock protein 90 (hsp90)
targeting metabolism for cancer therapy
Online Access:https://www.mdpi.com/2218-273X/10/1/135

Internet

https://www.mdpi.com/2218-273X/10/1/135

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