Dysregulated UPR and ER Stress Related to a Mutation in the <i>Sdf2l1</i> Gene Are Involved in the Pathophysiology of Diet-Induced Diabetes in the Cohen Diabetic Rat

Dysregulated UPR and ER Stress Related to a Mutation in the <i>Sdf2l1</i> Gene Are Involved in the Pathophysiology of Diet-Induced Diabetes in the Cohen Diabetic Rat

The Cohen Diabetic rat is a model of type 2 diabetes mellitus that consists of the susceptible (CDs/y) and resistant (CDr/y) strains. Diabetes develops in CDs/y provided diabetogenic diet (DD) but not when fed regular diet (RD) nor in CDr/y given either diet. We recently identified in CDs/y a deleti...

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Bibliographic Details
Main Authors: Chana Yagil, Ronen Varadi-Levi, Chen Ifrach, Yoram Yagil
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
type 2 diabetes
glucose
insulin
rodent model
diet
mechanism
Online Access:https://www.mdpi.com/1422-0067/24/2/1355

Internet

https://www.mdpi.com/1422-0067/24/2/1355

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