Novel chalcone-based fluorescent human histamine H3 receptor ligands as pharmacological tools
Novel fluorescent chalcone-based ligands at human histamine H3 receptors (hH3R) have been designed, synthesized and characterized. Compounds described are non-imidazole analogues of ciproxifan with a tetralone motif. Tetralones as chemical precursors and related fluorescent chalcones exhibit affinit...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-03-01
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| Series: | Frontiers in Systems Neuroscience |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2012.00014/full |