Elevated Osteopontin and Interferon Gamma Serum Levels and Increased Neutrophil-to-Lymphocyte Ratio Are Associated With the Severity of Symptoms in Schizophrenia

Elevated Osteopontin and Interferon Gamma Serum Levels and Increased Neutrophil-to-Lymphocyte Ratio Are Associated With the Severity of Symptoms in Schizophrenia

Inflammation and immune dysregulation could contribute to the pathogenesis of schizophrenia. Osteopontin (OPN) is a cytokine-like glycoprotein involved in inflammation and in modulating immune responses, and it can also directly modify the cytokine expression and survival of microglia. Furthermore,...

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Bibliographic Details
Main Authors: Márton Áron Kovács, Tamás Tényi, Réka Kugyelka, Lilla Prenek, Lídia Hau, Éva Erzsébet Magyar, Róbert Herold, Péter Balogh, Diána Simon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Psychiatry
Subjects:
osteopontin
cytokines
schizophrenia
the Positive and Negative Syndrome Scale
inflammation
antipsychotics
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00996/full

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https://www.frontiersin.org/article/10.3389/fpsyt.2019.00996/full

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