Development of Liver-on-Chip Integrating a Hydroscaffold Mimicking the Liver’s Extracellular Matrix

Development of Liver-on-Chip Integrating a Hydroscaffold Mimicking the Liver’s Extracellular Matrix

The 3Rs guidelines recommend replacing animal testing with alternative models. One of the solutions proposed is organ-on-chip technology in which liver-on-chip is one of the most promising alternatives for drug screening and toxicological assays. The main challenge is to achieve the relevant in vivo...

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Bibliographic Details
Main Authors: Taha Messelmani, Anne Le Goff, Zied Souguir, Victoria Maes, Méryl Roudaut, Elodie Vandenhaute, Nathalie Maubon, Cécile Legallais, Eric Leclerc, Rachid Jellali
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Bioengineering
Subjects:
organ-on-chip
liver
extracellular matrix
hydroscaffold
spheroid
Online Access:https://www.mdpi.com/2306-5354/9/9/443

Internet

https://www.mdpi.com/2306-5354/9/9/443

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