Complement System and Alarmin HMGB1 Crosstalk: For Better or Worse

Complement System and Alarmin HMGB1 Crosstalk: For Better or Worse

Our immune system responds to infectious (PAMPs) and tissue damage (DAMPs) signals. The complement system and alarmin High-Mobility Group Box 1 (HMGB1) are two powerful soluble actors of human host defense and immune surveillance. These systems involve molecular cascades and amplification loops for...

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Bibliographic Details
Main Authors: Christine Gaboriaud, Marie Lorvellec, Véronique Rossi, Chantal Dumestre-Pérard, Nicole M. Thielens
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
complement system
interplay
HMGB1
auto-immunity
lupus
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.869720/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.869720/full

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