The Pharmacokinetic Profile of Freeze-dried Cyclosporine A-Eudragit S100 Nanoparticle Formulation in Dogs

The pharmacokinetic profile of freeze-dried cyclosporine A-Eudragit S100 nanoparticles (CyA-S100-NP)was studied with a random two-way crossover study in dogs. The drug blood concentration was determined by internal standard HPLC method after oral administration of CyA-S100-NP and Neoral. Pharmacokin...

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Bibliographic Details
Main Authors: Yang Liu, Zhigang Fang, Yagen Chen, Jiankang Zhang, Xuenong Zhang, Qiang Hong
Format: Article
Language:English
Published: Tsinghua University Press 2011-03-01
Series:Nano Biomedicine and Engineering
Subjects:
Online Access:https://www.sciopen.com/article/10.5101/nbe.v3i1.p53-56