NLRP3/1-mediated pyroptosis: beneficial clues for the development of novel therapies for Alzheimer’s disease

NLRP3/1-mediated pyroptosis: beneficial clues for the development of novel therapies for Alzheimer’s disease

The inflammasome is a multiprotein complex involved in innate immunity that mediates the inflammatory response leading to pyroptosis, which is a lytic, inflammatory form of cell death. There is accumulating evidence that nucleotide-binding domain and leucine-rich repeat pyrin domain containing 3 (NL...

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Bibliographic Details
Main Authors: Bo Hu, Jiaping Zhang, Jie Huang, Bairu Luo, Xiansi Zeng, Jinjing Jia
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease; caspase-1; gsdmd; inflammasome; neuroinflammation; nlrp1; nlrp3; pyroptosis; therapeutic strategies
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=11;spage=2400;epage=2410;aulast=

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=11;spage=2400;epage=2410;aulast=

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