Application of modified Michaelis – Menten equations for determination of enzyme inducing and inhibiting drugs

Application of modified Michaelis – Menten equations for determination of enzyme inducing and inhibiting drugs

Abstract Background Pharmacokinetics (PK) is the process of absorption, distribution, metabolism and elimination (ADME) of drugs. Some drugs undergo zero-order kinetics (ethyl alcohol), first order kinetics (piroxicam) and mixed order kinetics (ascorbic acid). Drugs that undergo Michaelis-Menten met...

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Bibliographic Details
Main Author: Saganuwan Alhaji Saganuwan
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Pharmacology and Toxicology
Subjects:
Enzymology
Drug
Michaelis-Menten equation
Pharmacokinetics
Efficacy
Toxicity
Online Access:https://doi.org/10.1186/s40360-021-00521-x

Internet

https://doi.org/10.1186/s40360-021-00521-x

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