Evidence for a Role of CCR6+ T Cells in Chronic Thromboembolic Pulmonary Hypertension

Evidence for a Role of CCR6+ T Cells in Chronic Thromboembolic Pulmonary Hypertension

IntroductionPrevious studies have shown an increase of T cells and chemokines in vascular lesions of patients with chronic thromboembolic pulmonary hypertension (CTEPH). However, detailed characterization of these T cells is still lacking, nor have treatment effects been evaluated.MethodsWe included...

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Bibliographic Details
Main Authors: Denise van Uden, Thomas Koudstaal, Jennifer A. C. van Hulst, Thierry P. P. van den Bosch, Madelief Vink, Ingrid M. Bergen, Karishma A. Lila, Annemien E. van den Bosch, Paul Bresser, Mirjam Kool, Jan H. von der Thüsen, Rudi W. Hendriks, Karin A. Boomars
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
chronic thromboembolic pulmonary hypertension
immunology
T cell
cytokine
CCR6
CTLA4
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.861450/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.861450/full

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