SDF-1α/CXCR4 Axis Mediates The Migration of Mesenchymal Stem Cells to The Hypoxic-Ischemic Brain Lesion in A Rat Model

Objective: Transplantation of mesenchymal stem cells (MSCs) can promote functional recovery of the brain after hypoxic-ischemic brain damage (HIBD). However, the mechanism regulating MSC migration to a hypoxic-ischemic lesion is poorly understood. Interaction between stromal cell-derived factor-1α (...

Full description

Bibliographic Details
Main Authors: Qin Yu, Lizhen Liu, Jie Lin, Yan Wang, Xiaobo Xuan, Ying Guo, Shaojun Hu
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2015-01-01
Series:Cell Journal
Subjects:
Online Access:http://celljournal.org/library/upload/article/af_62638352254724343335824622324222265233446-Qin%20Yu.pdf