Hyperoside Suppresses Renal Inflammation by Regulating Macrophage Polarization in Mice With Type 2 Diabetes Mellitus

Hyperoside Suppresses Renal Inflammation by Regulating Macrophage Polarization in Mice With Type 2 Diabetes Mellitus

Accumulating evidence reveals that both inflammation and lymphocyte dysfunction play a vital role in the development of diabetic nephropathy (DN). Hyperoside (HPS) or quercetin-3-O-galactoside is an active flavonoid glycoside mainly found in the Chinese herbal medicine Tu-Si-Zi. Although HPS has a v...

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Bibliographic Details
Main Authors: Jialing Liu, Yanmei Zhang, Hongqin Sheng, Chunling Liang, Huazhen Liu, Jose Alberto Moran Guerrero, Zhaoyu Lu, Wei Mao, Zhenhua Dai, Xusheng Liu, Lei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
diabetic nephropathy
macrophage polarization
hyperoside
renal inflammation
Th1 cell
Treg cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.733808/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.733808/full

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