Application of a Small Protein-Coated Column to Trap, Extract and Enrich Carbamazepine Directly from Human Serum for Direct Chromatographic Analysis

Application of a Small Protein-Coated Column to Trap, Extract and Enrich Carbamazepine Directly from Human Serum for Direct Chromatographic Analysis

An automated solid phase extraction (SPE) protocol to determine carbamazepine in human serum has been developed and validated using a simple, rabid and sensitive liquid chromatography-based bio-analytical method. Extraction of carbamazepine was carried out using an on-line SPE tool of a short protei...

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Bibliographic Details
Main Authors: Heba Sonbol, Hager Ebrahim, Monika Malak, Ahmed Ali, Yasmine Aboulella, Ghada Hadad, Samy Emara, Ahmed Shawky
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Separations
Subjects:
carbamazepine
protein-coated ODS silica pre-column
human serum
on-line solid phase extraction
UV detection
Online Access:https://www.mdpi.com/2297-8739/10/2/71

Internet

https://www.mdpi.com/2297-8739/10/2/71

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