The Evaluation of DHPMs as Biotoxic Agents on Pathogen Bacterial Membranes

The Evaluation of DHPMs as Biotoxic Agents on Pathogen Bacterial Membranes

Herein, we present biological studies on 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) obtained via Biginelli reaction catalyzed by NH4Cl under solvent-free conditions. Until now, DHPMs have not been tested for biological activity against pathogenic <i>E. coli</i> strains. We tested 16 newly s...

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Bibliographic Details
Main Authors: Barbara Gawdzik, Paweł Kowalczyk, Dominik Koszelewski, Anna Brodzka, Joanna Masternak, Karol Kramkowski, Aleksandra Wypych, Ryszard Ostaszewski
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Membranes
Subjects:
3,4-dihydropyrimidin-2(1H)-ones (DHPMs) obtained by Biginelli reaction
DNA-N-glycosylase
Fpg protein formamidopyrimidine
lipopolysaccharide (LPS)
Online Access:https://www.mdpi.com/2077-0375/12/2/238

Internet

https://www.mdpi.com/2077-0375/12/2/238

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