The Evaluation of DHPMs as Biotoxic Agents on Pathogen Bacterial Membranes

The Evaluation of DHPMs as Biotoxic Agents on Pathogen Bacterial Membranes

Herein, we present biological studies on 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) obtained via Biginelli reaction catalyzed by NH4Cl under solvent-free conditions. Until now, DHPMs have not been tested for biological activity against pathogenic <i>E. coli</i> strains. We tested 16 newly s...

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Bibliographic Details
Main Authors:	Barbara Gawdzik, Paweł Kowalczyk, Dominik Koszelewski, Anna Brodzka, Joanna Masternak, Karol Kramkowski, Aleksandra Wypych, Ryszard Ostaszewski
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Membranes
Subjects:	3,4-dihydropyrimidin-2(1H)-ones (DHPMs) obtained by Biginelli reaction DNA-N-glycosylase Fpg protein formamidopyrimidine lipopolysaccharide (LPS)
Online Access:	https://www.mdpi.com/2077-0375/12/2/238

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