scMD facilitates cell type deconvolution using single-cell DNA methylation references

Abstract The proliferation of single-cell RNA-sequencing data has led to the widespread use of cellular deconvolution, aiding the extraction of cell-type-specific information from extensive bulk data. However, those advances have been mostly limited to transcriptomic data. With recent developments i...

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Bibliographic Details
Main Authors: Manqi Cai, Jingtian Zhou, Chris McKennan, Jiebiao Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05690-5