The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

Abstract Background Some studies in humans show that the concurrent use of clopidogrel and omeprazole decreases plasma clopidogrel active metabolite (CAM) concentrations and clopidogrel antiplatelet effects. Whether this drug interaction occurs in cats is unknown. Hypothesis We hypothesized that adm...

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Bibliographic Details
Main Authors: Christina Plante, Pamela M. Lee, Jillian M. Haines, O. Lynne Nelson, Stephanie E. Martinez, Michael H. Court
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of Veterinary Internal Medicine
Subjects:
Online Access:https://doi.org/10.1111/jvim.17198