The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

Abstract Background Some studies in humans show that the concurrent use of clopidogrel and omeprazole decreases plasma clopidogrel active metabolite (CAM) concentrations and clopidogrel antiplatelet effects. Whether this drug interaction occurs in cats is unknown. Hypothesis We hypothesized that adm...

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Bibliográfalaš dieđut
Váldodahkkit: Christina Plante, Pamela M. Lee, Jillian M. Haines, O. Lynne Nelson, Stephanie E. Martinez, Michael H. Court
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Wiley 2024-11-01
Ráidu:Journal of Veterinary Internal Medicine
Fáttát:
clopidogrel active metabolite
Multiplate Analyzer
Platelet Function Analyzer‐100
Plateletworks
Liŋkkat:https://doi.org/10.1111/jvim.17198

Interneahtta

https://doi.org/10.1111/jvim.17198

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