Progress in the study of mitochondrial dysfunction in pathogenesis of amyotrophic lateral sclerosis

Mitochondrial dysfunction plays an important role in the pathogenesis of amyotrophic lateral sclerosis(ALS). The mitochondrial dysfunction will cause severe oxidative stress and disruption in calcium homeostasis. The abnormally released mitochondrial DNA will induce cellular inflammation. These phen...

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Bibliographic Details
Main Author: LIU Liyang, LIU Qing, LIU Yaping, ZHANG Xue
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2023-02-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-2-332.pdf