Self-protection of individual CD4+ T cells against R5 HIV-1 infection by the synthesis of anti-viral CCR5 ligands.

It is well established that paracrine secretion of anti-viral CCR5 ligands by CD8+ and CD4+ T cells can block the infection of activated CD4+ T cells by R5 and dual-tropic isolates of HIV-1. By contrast, because CD4+ T cells can be infected by HIV-1 and at least some subsets secrete anti-viral CCR5...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Yongjun Guan, Sayed Abdelwahab, Roberta Kamin-Lewis, Anthony L DeVico, George K Lewis
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Public Library of Science (PLoS) 2008-01-01
Σειρά:PLoS ONE
Διαθέσιμο Online:http://europepmc.org/articles/PMC2567041?pdf=render