Self-protection of individual CD4+ T cells against R5 HIV-1 infection by the synthesis of anti-viral CCR5 ligands.

It is well established that paracrine secretion of anti-viral CCR5 ligands by CD8+ and CD4+ T cells can block the infection of activated CD4+ T cells by R5 and dual-tropic isolates of HIV-1. By contrast, because CD4+ T cells can be infected by HIV-1 and at least some subsets secrete anti-viral CCR5...

詳細記述

書誌詳細
主要な著者: Yongjun Guan, Sayed Abdelwahab, Roberta Kamin-Lewis, Anthony L DeVico, George K Lewis
フォーマット: 論文
言語:English
出版事項: Public Library of Science (PLoS) 2008-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC2567041?pdf=render