The increased effective connectivity from left middle occipital gyrus to right medial septum/diagonal bands in AD patients after donepezil intervention

The increased effective connectivity from left middle occipital gyrus to right medial septum/diagonal bands in AD patients after donepezil intervention

IntroductionDonepezil enhances the function of cholinergic nerves by increasing the concentration of acetylcholine, thereby improving clinical symptoms in patients with Alzheimer’s disease (AD). However, the neural mechanisms of how donepezil modulates the effective connectivity (EC) network of chol...

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Bibliographic Details
Main Authors: Ting Yang, Fuquan Wei, Yufei Guo, Mengxiao Zhu, Hongtao Hou, Zhongwei Guo, Xiaozheng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
cholinergic
functional magnetic resonance imaging
donepezil
effective connectivity
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1362790/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2024.1362790/full

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