Shallow Whole-Genome Sequencing of Cell-Free DNA (cfDNA) Detects Epithelial Ovarian Cancer and Predicts Patient Prognosis

Shallow Whole-Genome Sequencing of Cell-Free DNA (cfDNA) Detects Epithelial Ovarian Cancer and Predicts Patient Prognosis

Despite the progress in diagnostics and therapeutics, epithelial ovarian cancer (EOC) remains a fatal disease. Using shallow whole-genome sequencing of plasma cell-free DNA (cfDNA), we investigated biomarkers that could detect EOC and predict survival. Plasma cfDNA from 40 EOC patients and 20 health...

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Bibliographic Details
Main Authors: Seong Eun Bak, Hanwool Kim, Jung Yoon Ho, Eun-Hae Cho, Junnam Lee, Sung Min Youn, Seong-Woo Park, Mi-Ryung Han, Soo Young Hur, Sung Jong Lee, Youn Jin Choi
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
cfDNA
epithelial ovarian cancer
shallow whole-genome sequencing
plasma
prognosis
Online Access:https://www.mdpi.com/2072-6694/15/2/530

Internet

https://www.mdpi.com/2072-6694/15/2/530

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