Shallow Whole-Genome Sequencing of Cell-Free DNA (cfDNA) Detects Epithelial Ovarian Cancer and Predicts Patient Prognosis
Despite the progress in diagnostics and therapeutics, epithelial ovarian cancer (EOC) remains a fatal disease. Using shallow whole-genome sequencing of plasma cell-free DNA (cfDNA), we investigated biomarkers that could detect EOC and predict survival. Plasma cfDNA from 40 EOC patients and 20 health...
Main Authors: | Seong Eun Bak, Hanwool Kim, Jung Yoon Ho, Eun-Hae Cho, Junnam Lee, Sung Min Youn, Seong-Woo Park, Mi-Ryung Han, Soo Young Hur, Sung Jong Lee, Youn Jin Choi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/15/2/530 |
Similar Items
-
The cfDNA in early cancer detection
by: Hussein Adil Abid, et al.
Published: (2024-01-01) -
Deep cfDNA fragment end profiling enables cancer detection
by: Yulia V. Zhitnyuk, et al.
Published: (2022-01-01) -
Using cfDNA and ctDNA as Oncologic Markers: A Path to Clinical Validation
by: Jonathan Dao, et al.
Published: (2023-08-01) -
What fraction of cellular DNA turnover becomes cfDNA?
by: Ron Sender, et al.
Published: (2024-02-01) -
cfDNA Methylation Profiles and T-Cell Differentiation in Women with Endometrial Polyps
by: Xiao-Hong Li, et al.
Published: (2022-12-01)