Modelling the drivers of the spread of Plasmodium falciparum hrp2 gene deletions in sub-Saharan Africa

Modelling the drivers of the spread of Plasmodium falciparum hrp2 gene deletions in sub-Saharan Africa

Rapid diagnostic tests (RDTs) have transformed malaria diagnosis. The most prevalent P. falciparum RDTs detect histidine-rich protein 2 (PfHRP2). However, pfhrp2 gene deletions yielding false-negative RDTs, first reported in South America in 2010, have been confirmed in Africa and Asia. We developed...

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Bibliographic Details
Main Authors: Oliver J Watson, Hannah C Slater, Robert Verity, Jonathan B Parr, Melchior K Mwandagalirwa, Antoinette Tshefu, Steven R Meshnick, Azra C Ghani
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
pfhrp2-deletion
rapid diagnostic tests
mathematical modelling
mapping
Online Access:https://elifesciences.org/articles/25008

Internet

https://elifesciences.org/articles/25008

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