Targeting Neutrophil Apoptosis for Enhancing the Resolution of Inflammation

Targeting Neutrophil Apoptosis for Enhancing the Resolution of Inflammation

Resolution of acute inflammation is an active process that requires inhibition of further leukocyte recruitment and removal of leukocytes from inflamed sites. Emigrated neutrophils undergo apoptosis before being removed by scavenger macrophages. Recent studies using a variety of gene knockout, trans...

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Bibliographic Details
Main Authors: Driss El Kebir, János G. Filep
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Cells
Subjects:
neutrophils
apoptosis
phagocytosis
lipoxins
resolvins
annexin A1
TRAIL
cyclin-dependent kinases
Mcl-1
resolution of inflammation
Online Access:http://www.mdpi.com/2073-4409/2/2/330

Internet

http://www.mdpi.com/2073-4409/2/2/330

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