Reduced erythrocyte membrane polyunsaturated fatty acid levels indicate diminished treatment response in patients with multi- versus first-episode schizophrenia

Abstract Antipsychotic effects seem to decrease in relapsed schizophrenia patients and the underlying mechanisms remain to be elucidated. Based on the essential role of polyunsaturated fatty acids in brain function and the treatment of schizophrenia, we hypothesize that disordered fatty acid metabol...

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Bibliographic Details
Main Authors: Nana Li, Ping Yang, Mimi Tang, Yong Liu, Wenbin Guo, Bing Lang, Jianjian Wang, Haishan Wu, Hui Tang, Yan Yu, Xiangxin Wu, Cuirong Zeng, Ting Cao, Hualin Cai
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:npj Schizophrenia
Online Access:https://doi.org/10.1038/s41537-022-00214-2