Nature vs. Nurture: Defining the Effects of Mesenchymal Stromal Cell Isolation and Culture Conditions on Resiliency to Palmitate Challenge

As MSC products move from early development to clinical translation, culture conditions shift from xeno- to xeno-free systems. However, the impact of isolation and culture-expansion methods on the long-term resiliency of MSCs within challenging transplant environments is not fully understood. Recent...

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Bibliographic Details
Main Authors: Lauren K. Boland, Anthony J. Burand, Devlin T. Boyt, Hannah Dobroski, Lin Di, Jesse N. Liszewski, Michael V. Schrodt, Maria K. Frazer, Donna A. Santillan, James A. Ankrum
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01080/full