Validation of TYK2 and exploration of PRSS36 as drug targets for psoriasis using Mendelian randomization

Validation of TYK2 and exploration of PRSS36 as drug targets for psoriasis using Mendelian randomization

Abstract Psoriasis is a chronic inflammatory skin disorder with multiple causes, including genetic and environmental factors. Despite advances in treatment, there remains a need to identify novel therapeutic targets. A Mendelian randomization (MR) analysis was conducted to identify therapeutic targe...

Full description

Bibliographic Details
Main Authors: Xin Guo, Meng-jun Tao, XinCan Ji, MengQi Han, Yue Shen, Cheng Hong, HaoYang Guo, Wei Shi, Hui Yuan
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Psoriasis
Mendelian randomization
Drug targets
Genetics
Online Access:https://doi.org/10.1038/s41598-024-74148-3

Internet

https://doi.org/10.1038/s41598-024-74148-3

Similar Items