Protocol to derive human trophoblast stem cells directly from primed pluripotent stem cells

Summary: Human trophoblast stem cells (hTSCs) are useful for studying human placenta development and diseases, but primed human pluripotent stem cells (hPSCs) routinely cultured in most laboratories do not support hTSC derivation. Here, we present a protocol to derive hTSCs directly from primed hPSC...

Full description

Bibliographic Details
Main Authors: Yanxing Wei, Lu Xiao, Lishi Ma, Zhijian Wang, Liping Huang, Huiying Li, Guangjin Pan, Stephen J. Lye, Yongli Shan
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722005184